Kraken XBB.1.5

Happy New Year.

XBB.1.5 nicknamed Kraken, is the cause of an increase in Covid cases and hospitalizations in New York. This new variant is a recombinant or combined version of two Omicron variants and has an increased level of transmissibility and is highly immune evasive.

The Centers for Disease Control and Prevention (CDC) didn’t notice this variant until it  accounted for 40% of new infections in the United States. They were blindsided by the sudden surge. Cases have been doubling exponentially. From literally nowhere, XBB.1.5, aka the Kraken variant, has leapt to 40% of sequences on the US CDC’s weekly-updated variant tracker page. Last week, it wasn’t even listed as a variant.

Why are these figures so stunningly bad? For the simple reason that if you take a hyper-transmissable variant like XBB.1.5 and add a Delta variant like lethality to it, the country, or indeed the entire planet, could be facing an unprecedented and potentially irreversible disaster. The lethality of XBB.1.5 is unknown. It has a great affinity to ACE2, so likely it will be able to infect the lungs and the cardiovascular system with worse outcomes than previous Omicron variants.

XBB.1.5 has a “greatly enhanced” ability to bind to cells. It is a sub variant of Omicron but far more transmissible. “We’re projecting that it’s going to be the dominant variant in the Northeast region of the country and that it’s going to increase in all regions of the country,” said Dr. Barbara Mahon, director of the CDC’s proposed Coronavirus and Other Respiratory Viruses Division, in an interview with CBS News. More than 70% of infections in the regions spanning New Jersey through New England are now from XBB.1.5, the agency projected. Kraken is quickly spreading in Florida, Texas and Washington State.

Hospitalizations continue to tick upwards all across America. The Kraken is coming at a time when most of the public has abandoned masking and every other simple and basic mitigation measure. The Kraken is here to open the New Year. It is is resistant to many of the monoclonal antibody drugs that doctors had relied on earlier in the pandemic.  Omicron has caused more death than any other variant since the start of the pandemic simply because of the huge number of people infected.

The latest bivalent boosters appear to offer better “neutralizing activity” for Omicron variants, including XBB. So if you haven’t had your booster, it is advisable for the new year. The CDC has quietly begun recommending masking indoors but we all know that recommendation will go largely ignored and the lemmings will crowd together and infect one another. At home tests may prove less effective in detecting the new variant. One test, DxTerity’s saliva test for the virus, has proven itself useless.